Traceback (most recent call last):
  File "/opt/local/bin/certbot", line 33, in <module>
    sys.exit(load_entry_point('certbot==1.21.0', 'console_scripts', 'certbot')())
  File "/opt/local/bin/certbot", line 25, in importlib_load_entry_point
    return next(matches).load()
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/importlib/metadata.py", line 77, in load
    module = import_module(match.group('module'))
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/importlib/__init__.py", line 127, in import_module
    return _bootstrap._gcd_import(name[level:], package, level)
  File "<frozen importlib._bootstrap>", line 1014, in _gcd_import
  File "<frozen importlib._bootstrap>", line 991, in _find_and_load
  File "<frozen importlib._bootstrap>", line 975, in _find_and_load_unlocked
  File "<frozen importlib._bootstrap>", line 671, in _load_unlocked
  File "<frozen importlib._bootstrap_external>", line 843, in exec_module
  File "<frozen importlib._bootstrap>", line 219, in _call_with_frames_removed
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/certbot/main.py", line 2, in <module>
    from certbot._internal import main as internal_main
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/certbot/_internal/main.py", line 17, in <module>
    import josepy as jose
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/josepy/__init__.py", line 43, in <module>
    from josepy.json_util import (
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/josepy/json_util.py", line 14, in <module>
    from OpenSSL import crypto
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/OpenSSL/__init__.py", line 8, in <module>
    from OpenSSL import crypto, SSL
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/OpenSSL/crypto.py", line 17, in <module>
    from OpenSSL._util import (
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/OpenSSL/_util.py", line 6, in <module>
    from cryptography.hazmat.bindings.openssl.binding import Binding
  File "/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/cryptography/hazmat/bindings/openssl/binding.py", line 16, in <module>
    from cryptography.hazmat.bindings._openssl import ffi, lib
ImportError: dlopen(/opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/cryptography/hazmat/bindings/_openssl.abi3.so, 2): Symbol not found: _EVP_PKEY_size
  Referenced from: /opt/local/Library/Frameworks/Python.framework/Versions/3.8/lib/python3.8/site-packages/cryptography/hazmat/bindings/_openssl.abi3.so
  Expected in: dynamic lookup