Yes, these variants are now enabled by default in the python ports.
That does not mean you need to compile them from source. You will receive binaries if they are available.
Due to the mass switch to openssl 3 on Sunday, our build machines have an extreme backlog and may not yet have gotten around to building the python packages with these new variants. That will resolve itself within a few days.
If you wish to install the ports without these variants, you can:
sudo port install python27 -lto -optimizations
If you do this, you will have to compile from source because our build machines only build ports with their default set of variants.